ea0037ep592 | Obesity and cardiovascular endocrinology | ECE2015
Berta Eszter
, Zsiros Noemi
, Nagy Endre
, Paragh Gyorgy
, Bodor Miklos
Statins are effective treatment for the prevention of cardiovascular diseases and used extensively worldwide. However, adverse effects induced by statins are the major barrier of maximalising cardiovascular risk reduction. Hypothyroidism and administration of drugs metabolised on the same cytochrome P450 (CYPP450) pathways where statin biotransformation occurs represent a significant risk factor for statin induced adverse effects including myopathy. Simvastatin, atorvastatin a...